domain:A pair of annexin repeats may form one binding site for calcium and phospholipid.,function:Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.,similarity:Belongs to the annexin family.,similarity:Contains 4 annexin repeats.,tissue specificity:Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.,
nucleus,nuclear envelope,endoplasmic reticulum membrane,cytosol,plasma membrane,membrane,chromaffin granule membrane,extracellular exosome,
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
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