function:This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,PTM:C-terminal Ser or Thr residues may be phosphorylated.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.,
Cell membrane; Multi-pass membrane protein. Endosome. Agonist-binding promotes endocytosis.
Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
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