catalytic activity:Binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs.,function:May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,subcellular location:Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.,subunit:Homodimer.,
Cytoplasm . Cytoplasm, perinuclear region .
Blood,Colon,Testis,Uterus,
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