function:Acts as an anti-apoptotic factor and its absence increases cell death under normal and stress conditions. Can induce cell cycle arrest in the G1 or early S phase and this activity is independent of TP53/p53.,subcellular location:Accumulates in the nucleus in response to stress.,
Cytoplasm . Nucleus . Accumulates in the nucleus in response to stress. .
Highly expressed in colorectal and lung cancer tissues.
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