catalytic activity:ATP + 2 H(2)O = AMP + 2 phosphate.,cofactor:Calcium.,cofactor:Magnesium.,function:In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.,PTM:Palmitoylated in the N-terminal part.,PTM:The N-terminus is blocked.,similarity:Belongs to the GDA1/CD39 NTPase family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.,
Membrane ; Multi-pass membrane protein .
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
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