disease:Defects in IGLL1 are a cause of autosomal recessive non-Bruton type agammaglobulinemia [MIM:601495]. It is characterized by agammaglobulinemia and markedly reduced numbers of B cells.,online information:IGLL1 mutation db,similarity:Contains 1 Ig-like C1-type (immunoglobulin-like) domain.,subunit:Associates non-covalently with VPREB1.,tissue specificity:Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).,
Endoplasmic reticulum . Secreted . In pre-B cells, localizes predominantly to the endoplasmic reticulum. .
Expressed only in pre-B-cells and a special B-cell line (which is surface Ig negative).
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