function:Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.,induction:By phorbol 12-myristate 13-acetate (PMA).,miscellaneous:AR is a protein containing cysteines in disulfide linkage(s) that are essential for its biological activity. AR may contain oligosaccharides and/or lipid moieties that are not obligatory for the biological activity.,similarity:Belongs to the amphiregulin family.,similarity:Contains 1 EGF-like domain.,subunit:The immature precursor interacts with CNIH.,
Membrane; Single-pass membrane protein.
Brain,Pooled,
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