catalytic activity:CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.,function:Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.,online information:GlycoGene database,online information:ST6Gal I,pathway:Protein modification; protein glycosylation.,PTM:The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 29 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.,
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Liver,Lymph,Placenta,Skin,Spleen,Thymus,
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