function:Chaperone that expresses an ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subunit:Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1.,tissue specificity:Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.,
Mitochondrion . Mitochondrion inner membrane . Mitochondrion matrix .
Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is highly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors.
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