function:May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.,similarity:Contains 1 EGF-like domain.,tissue specificity:In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.,
[Epiregulin]: Secreted, extracellular space .; [Proepiregulin]: Cell membrane ; Single-pass type I membrane protein .
In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.