disease:Mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy (SMA) leading to the hypothesis that mutations in the NAIP locus may contribute to the SMA phenotype.,function:Prevents motor-neuron apoptosis induced by a variety of signals.,similarity:Contains 1 NACHT domain.,similarity:Contains 3 BIR repeats.,tissue specificity:Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.,
cytoplasm,basolateral plasma membrane,neuron projection,perikaryon,extracellular exosome,
Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.
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