disease:Defects in APOC2 are the cause of hyperlipoproteinemia type IB [MIM:207750]. It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.,function:Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly.,similarity:Belongs to the apolipoprotein C2 family.,tissue specificity:Secreted in plasma.,
Secreted .
Liver and intestine.
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