developmental stage:Expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels.,function:May have a functional role during normal fetal development.,tissue specificity:Expressed in the fetal brain, lung, liver and kidney at varying low levels.,
Cytoplasm . Nucleus .
Expressed in the neuronal cells of the cerebrum and cerebellum, spermatocytes of the testis, pancreatic cells and also the heart. Expressed in both primary and metastatic neuroblastomas and in thyroid tumors (at protein level). Expression is associated with poor prognosis in neuroblastoma. Expressed in the fetal brain, lung, liver and kidney at varying low levels.
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