domain:The N-terminal IgGFc-binding region is primate-specific.,function:May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa.,similarity:Contains 12 TIL (trypsin inhibitory-like) domains.,similarity:Contains 13 VWFD domains.,subunit:Interacts with the Fc portion of IgG and with MUC2.,tissue specificity:Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level).,
Secreted .
Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level).