catalytic activity:Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.,disease:Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.,function:Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.,similarity:Belongs to the transaldolase family.,similarity:Belongs to the transaldolase family. Type 1 subfamily.,
Cytoplasm .