catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays a role in NF-kappa B activation.,PTM:May be phosphorylated by MAP3K2 and MAP3K3.,PTM:Proteolytically cleaved by during Fas-induced apoptosis. Cleavage at Asp-388 and Asp-426.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subunit:Interacts with PRKCB (By similarity). Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.,
Cytoplasm. Membrane ; Peripheral membrane protein .
Expressed in hair follicles and skin.
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