enzyme regulation:Inhibited by tolrestat.,function:Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.,
Lysosome . Secreted . Secreted through a lysosome-mediated non-classical pathway.
Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
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