function:May play a role in organizing the actin cytoskeleton of the brain cells.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Binds actin.,tissue specificity:Predominantly expressed in brain.,
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection . Cell projection, lamellipodium . Cytoplasm, cytosol. A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity). .
Ubiquitous. Detected throughout the brain.