domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,domain:The thioredoxin domain lacks the 2 redox-active cysteines, suggesting that it lacks thioredoxin activity.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Widely expressed.,
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Mitochondrion membrane . Localizes to endoplasmic reticulum mitochondria-associated membrane (MAMs) that connect the endoplasmic reticulum and the mitochondria. .
Widely expressed.
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