catalytic activity:L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.,function:Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.,pathway:Nucleotide-sugar biosynthesis; UDP-N-acetyl-D-glucosamine biosynthesis; D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.,similarity:Contains 1 glutamine amidotransferase type-2 domain.,similarity:Contains 2 SIS domains.,subunit:Homotetramer .,tissue specificity:Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.,
cytosol,extracellular exosome,
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
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