function:Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis.,similarity:Belongs to the DNA mismatch repair mutS family.,subunit:Heterooligomer of MSH4 and MSH5. Interacts with HJURP.,tissue specificity:Ubiquitous, but highly expressed in testis, and thymus.,
synaptonemal complex,mismatch repair complex,
Widely expressed, with high levels in testis and ovary, including granulosa cells (PubMed:9740671, PubMed:28175301). Also expressed in fetal ovary and adrenal gland (PubMed:28175301).
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