Membrane ; Single-pass membrane protein . Cytoplasm . Secreted, extracellular space, extracellular matrix . Appears as reticular-like structures throughout the cytoplasm and adjacent to the plasma membrane. In proliferation and hypertrophic chondrocytes, detected intracellulary and in the pericellular extracellular matrix. In primary spongiosa, detected only in the extracellular matrix. .
Expressed in cartilage.
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