NOVA2 rabbit pAb

disease:Autoantigen in the paraneoplastic opsoclonus myoclonus ataxia (POMA), a paraneoplastic neurological syndrome/disorder (PNS/D) associated with breast cancer, fallopian cancer, and SCLCa and characterized primarily by loss of inhibitory control of motor neurons in the spinal cord and brainstem. Recognized by the IgG autoantibody ANNA-2 (also called anti-Ri).,domain:The third KH domain (KH3) recognizes specifically 5'-UCAY-3'.,function:May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA.,similarity:Contains 3 KH domains.,subunit:Interacts with PTBP2.,tissue specificity:Brain. Expression restricted to astrocytes.,