caution:Was reported (PubMed:10428810) to have a protein kinase activity and to autophosphorylates on Ser-385 and Thr-389.,function:TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.,PTM:Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.,similarity:Belongs to the TFIIF alpha subunit family.,subunit:Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2 and CTDP1. Interacts with TAF6/TAFII80.,
Nucleus.
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