function:May function as a homophilic adhesion molecule. Functions in leukocyte-endothelial cell interactions during leukocyte extravasation, and in particular, at the diapedesis step. Does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis.,PTM:O-glycosylated.,similarity:Belongs to the CD99 family.,tissue specificity:Expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis and uterus. Lower expression seen in thymus. Expressed in E18 uterus and placenta.,
Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell junction .
Expressed in many tissues, with low expression in thymus.
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