function:Involved in the transport and maturation of proteins.,similarity:Belongs to the cornichon family.,
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). .
Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).