function:Involved in acrosome biogenesis.,tissue specificity:Isoform 1 highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.,
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane ; Single-pass type I membrane protein . In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. .
Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.
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