catalytic activity:ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA.,function:Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,tissue specificity:Highly expressed in kidney, heart and brain, but low in liver.,
Cytoplasm, cytosol .
Highly expressed in kidney, heart and brain, but low in liver.
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