catalytic activity:ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.,function:May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.,PTM:Phosphorylated.,similarity:Contains 1 PI5K domain.,subcellular location:Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis.,
Endoplasmic reticulum . Cytoplasm .
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