domain:Each of the two internal repeats contains five hydrophobic transmembrane segments (S1, S2, S3, S5, S6) and one positively charged transmembrane segment (S4). S4 segments probably represent the voltage-sensor and are characterized by a series of positively charged amino acids at every third position.,function:May function as one of the major voltage-gated Ca(2+) channel (VDCC) across the plasma membrane.,similarity:Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.,subunit:Dimer .,tissue specificity:Highest expression found in the heart and kidney, and lowest expression found in the spleen.,
Lysosome membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein .
Highest expression found in the heart and kidney, and lowest expression found in the spleen.
下载说明书
