caution:The mouse ortholog has been suggested to be a GPI-anchored protein, but no GPI-anchor is detected by prediction methods.,function:Plays a key role in the lipolytic processing of chylomicrons.,polymorphism:The missense variant Arg-56 may be associated with severe hypertriglyceridemia and chylomicronemia.,similarity:Contains 1 UPAR/Ly6 domain.,subcellular location:Localized at the cell surface.,subunit:Binds with high affinity to high-density lipoprotein (HDL) (By similarity). Binds to lipoprotein lipase (LPL), chylomicrons and APOA5.,
Apical cell membrane ; Lipid-anchor, GPI-anchor . Basolateral cell membrane ; Lipid-anchor, GPI-anchor . Cell membrane ; Lipid-anchor, GPI-anchor .
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