function:Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.,induction:Up-regulated by basic fibroblast growth factor (bFGF) in gastric cancer cells.,similarity:Belongs to the KCMF1 family.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 ZZ-type zinc finger.,tissue specificity:Spleen, small intestine, ovary, peripheral blood, lung, kidney and pancreas. Expressed at low levels in the thymus, prostate, testis, colon, heart, brain, placenta and liver.,
Spleen, small intestine, ovary, peripheral blood, lung, kidney and pancreas. Expressed at low levels in the thymus, prostate, testis, colon, heart, brain, placenta and liver.