function:May block the elongation and depolymerization of the actin filaments at the pointed end.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the tropomodulin family.,similarity:Contains 1 WH2 domain.,subunit:Able to bind to tropomyosin.,tissue specificity:Specifically expressed in heart and skeletal muscles. Not expressed in other tissues.,
Cytoplasm, myofibril, sarcomere . Cytoplasm, myofibril . Cytoplasm, myofibril, sarcomere, M line . Cytoplasm, cytoskeleton . Colocalizes with actin filaments in sarcomeres. Detected close to the M line. .
Specifically expressed in heart and skeletal muscles, with higher levels in heart (at protein level). Not expressed in other tissues.