function:May have a role in a signaling pathway. Could act as a tumor suppressor.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,tissue specificity:Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.,
Cytoplasm .
Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues. Expressed in the epidermis, epidermal keratinocytes, dermal fibroblasts and melanocytes (PubMed:23333244, PubMed:26203640).
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