function:Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins.,similarity:Belongs to the SAP18 family.,subunit:Forms a complex with SIN3A and HDAC1.,tissue specificity:Ubiquitous.,
Nucleus . Cytoplasm . Nucleus speckle . Shuttles between the nucleus and the cytoplasm (PubMed:16314458). Colocalizes with ACIN1 and SRSF2 in nuclear speckles (PubMed:20966198). .
Ubiquitous.
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