domain:C2 domain 1 is involved in binding calcium and phospholipids.,function:May be involved in constitutive membrane trafficking including dynein-dependent intracellular vesicle transport. In vitro, binds calcium and phospholipids.,similarity:Contains 2 C2 domains.,subunit:Interacts with cytoplasmic dynein light chain TCTEL1/TCTEX1.,tissue specificity:Widely expressed with highest levels in brain and kidney.,
Cytoplasm. Cytoplasmic granule . Cell membrane ; Peripheral membrane protein . Translocates to the plasma membrane in a calcium-dependent manner. .
Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level).
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