function:Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.,similarity:Belongs to the tektin family.,subcellular location:In sperm, observed in a discontinuous punctate pattern in the flagellum and in the postacrosomal head region.,tissue specificity:Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.,
Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme . Cytoplasm, cytoskeleton, microtubule organizing center . Colocalized with CCDC172 at the perinuclear region. .
Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.
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