catalytic activity:2-hydroxyphytanoyl-CoA = pristanal + formyl-CoA.,cofactor:Binds 1 magnesium ion per subunit.,cofactor:Binds 1 thiamine pyrophosphate per subunit.,function:Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.,pathway:Lipid metabolism; fatty acid metabolism.,similarity:Belongs to the TPP enzyme family.,subunit:Homotetramer.,tissue specificity:Expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle.,
Peroxisome .
Widely expressed.
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