function:May be a Rab21 guanine exchange factor and regulate endosome dynamics.,similarity:Contains 1 VPS9 domain.,similarity:Contains 11 ANK repeats.,subcellular location:Mainly localized to early endosomes in the perinuclear region.,subunit:Interacts with RAB21 and RAB5, with a strong preference for RAB21.,
Early endosome . Late endosome . Cytoplasmic vesicle membrane . Lysosome . Cell membrane . Melanosome . Colocalizes with VAMP7 in transport vesicles in the shaft of hippocampal neurons (By similarity). .
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