Transports PGD2, as well as PGE1, PGE2 and PGF2A. Mediates the clearance of prostaglandins from the circulation through uptake across cell membrane which allows cytoplasmic oxidation and prostaglandin signal termination . May mediate the release of newly synthesized prostaglandins from cells and the transepithelial transport of prostaglandins (Probable).
Cell membrane ; Multi-pass membrane protein .
Ubiquitous. Significant expression observed in ling, kidney, spleen, and heart.
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