GTPase activator for the nuclear Ras-related regulatory proteins Rap1 and Rap2 in vitro, converting them to the putatively inactive GDP-bound state . Affects cell cycle progression (By similarity).
Nucleus . Cytoplasm, perinuclear region . Endomembrane system; Peripheral membrane protein . Mostly localized in the perinuclear membraneous region. .
Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
下载说明书
