acute inflammatory response, defense response, acute-phase response, inflammatory response, response to wounding,
[Soluble CD163]: Secreted .; Cell membrane ; Single-pass type I membrane protein . Isoform 1 and isoform 2 show a lower surface expression when expressed in cells.
Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.