proteolysis, response to wounding, regulation of cell death, regulation of apoptosis, regulation of programmed cell death,
Lysosome . Melanosome . Secreted, extracellular space . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity). .
Expressed in the stratum spinosum of the epidermis. Weak expression is detected in the stratum granulosum.
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