cell morphogenesis, cell morphogenesis involved in differentiation, embryonic epithelial tube formation, neural tube formation, neural tube closure, morphogenesis of an epithelium, cell motion, cytoskeleton organization, axonogenesis,axon guidance, embryonic development ending in birth or egg hatching, primary neural tube formation,morphogenesis of embryonic epithelium, neural tube development, actin filament-based process, cell projection organization, actin cytoskeleton organization, neuron differentiation, neuron projection development, cellular component morphogenesis, cell part morphogenesis, tube lumen formation, tube morphogenesis, tube development,chordate embryonic development, embryonic morphogenesis, neuron development, cell morphogenesis involved in neuron differentiation, tissue morphogenesis, neuron projection morphogenesis, cell projection morphogenesis,epithelium development, epithelial tube morphogenesis, tube closure,
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction . Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
Highly expressed in platelets.
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