catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the GST superfamily. Pi family.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:Homodimer.,
Cytoplasm . Mitochondrion . Nucleus . The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Brain,Cajal-Retzius cell,Colon carcinoma,Fetal brain cortex,Platelet,Urinar
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