function:One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.,similarity:Belongs to the FAM10 family.,similarity:Contains 1 STI1 domain.,similarity:Contains 3 TPR repeats.,subunit:Homotetramer. Interacts with HSC70 as well as DNAJ homologs and HSP90.,
Cytoplasm .
Colon mucosa,Epithelium,Fet
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