DNA metabolic process, telomere organization, telomere assembly, telomere formation via telomerase, positive regulation of catalytic activity, positive regulation of molecular function, chromosome organization, regulation of transferase activity, positive regulation of transferase activity, regulation of telomerase activity, positive regulation of telomerase activity,
Nucleus, Cajal body . Chromosome, telomere . Chromosome . Released from telomerase RNA template component (TERC) in mitotic cells coincident with delocalization from Cajal bodies (PubMed:26170453). In response to DNA damage, localizes to sites of DNA double-strand breaks following phosphorylation by ATM (PubMed:26734725, PubMed:27715493). .
Expressed in all tissues and cell lines examined.
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