catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:The activated kinase acts on a variety of targets.,PTM:Autophosphorylated when activated by CDC42/p21.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CRIB domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1 (By similarity). Interacts with the androgen receptor.,
Cytoplasm. Nucleus. Cotranslocates into nucleus with AR in response to androgen induction.
Selectively expressed in brain and testis, with lower levels in multiple tissues including prostate and breast.
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