domain:The RING finger domain and the coiled-coil region are required for the apoptosis-inducing activity.,function:May play a role as a tumor suppressor. Implicated in the cell death mechanism.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.,
Cytoplasm . Nucleus . Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies (By similarity). .
Brain,Liver,Lung,
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