catalytic activity:Obtusifoliol + 3 O(2) + 3 NADPH = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP(+) + 4 H(2)O.,cofactor:Heme group.,function:Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.,pathway:Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 1/6.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostrate, liver, kidney and lung.,
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
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